Noel
Christmas Eve in New York, and the lonely divorced publisher, Rose Collins, needs a miracle to improve the health of her mother, interned in a hospital with Alzheimers. She feels sorry for another patient and meets his visitor. Meanwhile, Nina Vasquez breaks her engagement with her beloved fiancé Mike due to his suffocating jealousy, but misses him. Mike is stalked by a stranger, bartender Artie Venzuela. The poor Jules arranges to spend Christmas Eve in the hospital, where he spent the best Christmas of his life when he was a teenager. The lives of some of these characters cross with others along the night.
Susan Sarandon
Rose Collins
Paul Walker
Mike Riley
Penélope Cruz
Nina Vasquez
Alan Arkin
Artie
Marcus Thomas
Jules Calvert
Sonny Marinelli
Dennis
Daniel Sunjata
Marco
Chazz Palminteri
Arizona
Robin Williams
Charlie Boyd / The Priest
Rob Daly
Paul
John Doman
Dr. Baron
Billy Porter
Randy
Carmen Ejogo
Dr. Batiste
Donna Hanover
Debbie Carmichael
Merwin Mondesir
Glenn
Una Kay
Helen
Sonia Benezra
Aunt Sonya
Marcia Bennett
Nurse Stein
Howard Rosenstein
ER Doctor
Jane Wheeler
Karen
David Julian Hirsh
Barton
Marguerite Kinh
Mrs. Lee
Arthur Holden
Piano Player
Maurizio Terrazzano
Tom
Rachelle Lefevre
Holly
Erika Rosenbaum
Merry
Charles Rosenblum
Coffee Vendor
Victoria Sanchez
Young Mother
Scott Faulconbridge
Man in Front Row
Budd Mishkin
NY1 Reporter
Carmen Echeverria
Young Girl
Gianpaolo Venuta
Young Guy
Nicholas Haze
Waiter
Ruth Chiang
Nurse Woo
Kevin Ryder
Bartender
Andy Bradshaw
Security Guard #1
Robert Newton Brown
Security Guard #2
Bill Corday
Meek Man
Jennifer Seguin
Young Woman
Lindsay Owen Pierre
Friend
David Schaap
Man with Head Injury
Lynne Adams
Head ER Nurse
Kathleen Mackey
Heather
Donna Giaimo
Singing Nun of the Daughters of St. Paul
Fay Josephine Pele
Singing Nun of the Daughters of St. Paul
Bridget Charles Ellis
Singing Nun of the Daughters of St. Paul
Mary R.G. Grissom
Singing Nun of the Daughters of St. Paul
Kathryn J. Hermes
Singing Nun of the Daughters of St. Paul
Bernadette M. Reis
Singing Nun of the Daughters of St. Paul
Margaret Timothy Sato
Singing Nun of the Daughters of St. Paul
Patricia C. Shaules
Singing Nun of the Daughters of St. Paul
Patricia C. Shaules
Singing Nun of the Daughters of St. Paul
Nancy M. Usselmann
Singing Nun of the Daughters of St. Paul
Christina M. Wegendt
Singing Nun of the Daughters of St. Paul
Gabriella Palminteri
Girl in Red Coat
James Callaghan
Extra (uncredited)
Isabelle Champeau
Party Guest (uncredited)
Lucinda Davis
Nurse Gomez (uncredited)
Francesco Giannini
Family member (uncredited)
Chantal Lonergan
Joy (uncredited)
Dante Palminteri
Boy in Hospital (uncredited)
Adrianne Richards
Nurse Kline (uncredited)